Effect of Alfacalcidol to Respiratory Infection and Immune Response of Indonesian Elderly

• Status: Unknown status
• Trial end date: 2017-12-15
• Target enrollment: 0
• Participant gender: All

Summary

Vitamin D has been known to influence immune response through Vitamin D Receptor in Immune Cells, but only few has been known about the effect alfacalcidol, a vitamin D analog to immune system. In elderly, immune disregulation or immunosenecence have great impact to infection response. This study is aimed to determine the effect of alfacalcidol supplementation in vitro and in vivo to respiratory infection incidence and inflammatory markers, as well as T cell lymphocyte subset in Indonesian elderly patients.

• Phase: Phase 4
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Indonesia University
• Treatments: Alfacalcidol; Cholecalciferol; Hydroxycholecalciferols

Criteria

Inclusion Criteria:

• Elderly age more than 60

• Willing to join research

Exclusion Criteria:

• In acute infection

• Using NSAID or steroid

• Liver failure

• Hypercalcemia