Effect of Anesthesia Technique on Early Outcome in Diabetic Patients Undergoing Lower Extremity Amputation

• Status: Recruiting
• Trial end date: 2021-09-01
• Target enrollment: 0
• Participant gender: All

Summary

The aim of this study was to compare

1. early prognosis (mortality, morbidity)

2. changes in concentrations of serum syndecan-1,partial pressure of oxygen(on arterial blood gas analysis), perioperative transfusion, intraoperative vasopressor use between general anesthesia and nerve block in diabetic patients undergoing limb amputation surgery as a prospective randomized trial.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Yonsei University
• Treatments: Anesthetics

Criteria

Inclusion Criteria:

• 1. Patients undergoing diabetic foot limb amputation.

• 2. Patients aged 20 or older and who meet American Society of Anesthesiologists (ASA) physical class 3-4

Exclusion Criteria:

• 1. patients with dementia or cognitive impairment

• 2. Patients who had previously undergone diabetic foot limb amputation within 1 month.

• 3. If the subject includes a person who can not read the written consent (eg, illiterate, foreigner, etc.)

• 4. pregnant or lactating women

• 5. Contraindications to nerve block (infection of the injection site, no cooperation, patient rejection, history of allergy ro local anesthetics)

• 6. Relative contraindications to general anesthesia (if difficult airways are expected, history of malignant hyperthermia, moderate or severe asthma)