Effect of Antihypertensive Agents Over Sleep Apnea
Status:
Completed
Trial end date:
2016-02-01
Target enrollment:
Participant gender:
Summary
Obstructive sleep apnea and hypertension are well-known cardiovascular risk factors. Their
control could reduce the burden of heart disease across populations. There are several drugs
to control hypertension, but the only consistently beneficial treatment to reduce apneas is
continuous positive airway pressure. The demonstration that one drug could improve sleep
apnea and hypertension would support a novel approach in the treatment of both diseases. The
role of fluid retention in sleep apnea is known for several decades. The role of diuretics is
well established in hypertension but was never appropriately tested in sleep apnea. Besides
to test the efficacy of these drugs, this study will help to understand the mechanisms that
link hypertension and sleep apnea and its treatment.