Effect of Antiinflammatory Treatment Versus Hand Training on Neuropsychiatric Comorbidity in RA-patients
Status:
Recruiting
Trial end date:
2025-09-01
Target enrollment:
Participant gender:
Summary
The purpose of this study is to investigate how RA affect the brain structures in RA-patients
and if anti-inflammatory treatment that target TNF-α or JAK OR physical training of hands has
positive impact on neuropsychiatric symptoms and morphological changes in the brain caused by
the disease.
The goal of this research project is to improve the knowledge of morphological changes in
brain developed in connection to RA and to identify clinical and serological markers to
predict development of those changes and finally, to investigate if anti-rheumatic
interventions counteract destructive processes in the central nervous system (CNS) and
improve the patient's health with respect to functionality, pain experience and psychological
well-being.