Effect of Antimicrobial Treatment of Acute Otitis Media on the Intestinal Microbiome in Children
Status:
Unknown status
Trial end date:
2020-03-01
Target enrollment:
Participant gender:
Summary
This is a randomized, controlled trial studying the effects of various antimicrobial
treatments on the intestinal microbiome of small children. The participating children with
acute otitis media are treated wither with amoxicillin, amoxicillin-clavulanate or without
antibiotics. The children with allergy to amoxicillin receive a course of macrolide and they
will be monitored as a separate group. The main outcomes of this trial are the changes in the
intestinal microbiome after the treatment.