Effect of Antioxidant Cocktail in Beta-thalassemia/Hb E Patients

• Status: Completed
• Trial end date: 2011-06-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to determine the efficacy of antioxidant cocktails on the alleviation of oxidative stress and iron overload in beta-thalassemia/Hb E patients.

• Phase: N/A
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Mahidol University
• Collaborator: ChaingMai University
• Treatments: Acetylcysteine; alpha-Tocopherol; Antioxidants; Deferiprone; N-monoacetylcystine; Tocopherols; Tocotrienols; Vitamin E; Vitamins

Criteria

Inclusion Criteria:

1. age between 18-50 years

2. hemoglobin level between 6-9 g/dL during screen visit

3. WHO performance status grade 0-2

4. signed in informed consents prior to the study entry.

Exclusion Criteria:

1. receiving iron chelator and blood transfusion.

2. pregnancy or breastfeeding

3. receiving other drugs except folic acid at least 30 days before study.