Effect of Aromatase Inhibitors on Breast Magnetic Resonance Imaging (MRI)
Status:
Completed
Trial end date:
2010-09-01
Target enrollment:
Participant gender:
Summary
This study is a primary investigation to determine the usefulness and safety of a short
course of a relatively high dose of letrozole (a medication used to decrease the female
hormone estrogen which is produced locally inside the breast after menopause) in improving
the performance of of breast MRI (Magnetic Resonance Imaging). The inhibition of estrogen in
the breast by letrozole might help better identifying of suspicious areas in the breast and
could assist radiologists in distinguishing between benign breast areas and cancer tissue.
This might help reducing the rate of call backs and unnecessary biopsies for patients. We
expect to enroll 20 healthy postmenopausal women in this study.