Effect of Atorvastatin on Fractional Flow Reserve in Coronary Artery Disease
Status:
Completed
Trial end date:
2018-11-01
Target enrollment:
Participant gender:
Summary
Natural course of intermediate coronary artery disease (CAD) is very important to predict the
prognosis of the patient with such disease.
Several studies have well demonstrated the beneficial effect of lipid-lowering therapy on the
progression of CAD with the modification of lipid profiles.
This effect can be also explained by intravascular ultrasound (IVUS) or optical coherence
tomography. However, the effect of plaque modification on coronary physiology has been rarely
evaluated.
This research is to evaluate the change of intermediate or nonculprit coronary lesion on
lipid-lowering therapy via IVUS(optional) and FFR.
Phase:
Phase 3
Details
Lead Sponsor:
Keimyung University Dongsan Medical Center
Collaborators:
Inje University Seoul National University Hospital Ulsan University Hospital