Effect of Beta Blockade on Left Ventricular Remodeling and Function in Moderate to Severe Asymptomatic Aortic Regurgitation

• Status: Completed
• Trial end date: 2014-09-01
• Target enrollment: 0
• Participant gender: All

Summary

The primary objective of this study is to evaluate the effect of beta-blocker on left ventricular (LV) remodeling in asymptomatic patients with moderate to severe aortic regurgitation.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Oslo University Hospital
• Collaborators: Haukeland University Hospital; University Ghent; University Hospital, Akershus; University Hospital, Gentofte, Copenhagen
• Treatments: Metoprolol

Criteria

Inclusion Criteria:

• Moderate to severe aortic valve insufficiency

• Asymptomatic

Exclusion Criteria:

• Arrhythmia

• Other severe valve disease