Effect of Beta Blocker Treatment on Endothelial Function in Patients With Type 2 Diabetes or Chronic Heart Failure
Status:
Completed
Trial end date:
2007-10-01
Target enrollment:
Participant gender:
Summary
The aim of this study is to evaluate the effect of the two different beta blockers metoprolol
and carvedilol on endothelial function in patients with either type two diabetes or chronic
heart failure.
Hypothesis: 1* Carvedilol compared to metoprolol has a favourable effect on endothelial
function.
2* Carvedilol compared to metoprolol has a favourable effect on insulin stimulated
endothelial function.
The study is conducted as an open parallel group study. Endothelial function and insulin
stimulated endothelial function was evaluated before and after a two months treatment period
with either of the two beta blockers.