Effect of Betamethasone Gel and Lidocaine Jelly on Sore Throat, Cough and Hoarseness of

• Status: Completed
• Trial end date: 2013-03-01
• Target enrollment: 0
• Participant gender: All

Summary

ABSTRACT:

The aim of this study was to investigate the effect of betamethasone gel and lidocaine jelly (over tracheal tube cuff) compared with distilled water on the post intubation syndrome incidence. This study has not been carried out in Iran.

99 patients of either sex undergoing elective surgery were recruited in a single blind randomized study. The patients, using randomization table, were divided into three groups. Anesthetics and medications used during surgery were similar for all the patients.

For the all patients, the incidence of postoperative sore throat, cough and hoarseness of the voice in the different follow-up periods (1, 6 and 24 hours) based on the different types of medications were obtained.

• Phase: Phase 3
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Tehran University of Medical Sciences
• Collaborator: Islamic Azad University, Tehran
• Treatments: Betamethasone; Betamethasone benzoate; Betamethasone sodium phosphate; Betamethasone Valerate; Betamethasone-17,21-dipropionate; Lidocaine

Criteria

Inclusion Criteria:

1. 50 years15 years

2. no acute upper respiratory infections and no sore throat

3. candidate for elective surgery unrelated to the throat

4. The lack of airways difficulties

5. candidate for general anesthesia with intubation

6. no contraindications for receiving steroid

7. surgery time < 240 minutes

8. intubation up to 2 times

9. tracheal tube cuff pressure = 25-30 cm H2o

10. fasting for 8-6 hours prior to surgery

11. ASA I and ASAII and

12. Surgery under general anesthesia and endotracheal intubation

Exclusion Criteria:

1. use of nasogastric tube or throat packs

2. patients with upper respiratory tract infection

3. patients on steroid therapy were excluded from the study