Overview

Effect of Body-mass Index (BMI) on Median Effective Dose of Intrathecal Hyperbaric Bupivacaine

Status:
Completed

Trial end date:
2010-12-01

Target enrollment:
0

Participant gender:
All

Summary

The effect of Body-mass index (BMI) on requirements of local anesthetics used in spinal anesthesia has not been well established. The investigators tried to quantify the effect of BMI on spinal anesthesia by comparing the median effective dose of intrathecal bupivacaine between two different BMI groups.

Phase:

N/A

Accepts Healthy Volunteers?

Details

Lead Sponsor:

Seoul Medical Center

Treatments:

Bupivacaine
Epinephrine
Epinephryl borate
Racepinephrine

Criteria

Inclusion Criteria:

- Patients undergoing elective total knee replacement arthroplasty

Exclusion Criteria:

- Patients with previous spine surgery, diabetic and other neuropathy, skin infection at
the site of injection, allergy to bupivacaine and other common contraindications for
spinal anesthesia were excluded from this study.

- The patients with height less than 140 cm or more than 160 cm, body-mass index (BMI)
less than 20 or greater than 35 were also excluded.