Effect of Broccoli Sprout Extract on Keratinocyte Differentiation in Normal Skin

• Status: Completed
• Trial end date: 2016-12-01
• Target enrollment: 0
• Participant gender: All

Summary

Adult participants will apply a broccoli sprout extract-jojoba oil compound to one arm every night under occlusion for 1 week. Jojoba oil alone will be applied to the other arm. At the end of 1 week, a 6mm punch biopsy will be taken from both arms and analyzed via polymerase chain reaction (PCR) and immunohistochemistry for differences in various skin proteins.

• Phase: Phase 1
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Johns Hopkins University

Criteria

Inclusion Criteria:

• Able to attend 3 visits at the designated times.

Exclusion Criteria:

• Pregnant

• Known allergy to broccoli, lidocaine, or epinephrine