Effect of Carum Carvi on Thyroid Hormones and TSH Level

• Status: Unknown status
• Trial end date: 1969-12-31
• Target enrollment: 0
• Participant gender: All

Summary

Carum Carvi has been frequently used in traditional medicine for a variety of disease ranging from dyspepsia to Alzheimer's disease.We observed high TSH levels in few patients with thyroid cancer who receiving Carum Carvi despite being on suppressive dose of levothyroxin. TSH level returned to normal after discontinuation of the Carum carvi. This observation led to a pilot study for evaluation of the effect of carum carvi on thyroid function.

• Phase: Phase 1/Phase 2
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Mashhad University of Medical Sciences
• Collaborator: Pharmaceutical Research Center
• Treatments: Hormones

Criteria

Inclusion Criteria:

• Age 18-65

• Hypothyroid patients under treatment with levothyroxin

• Normal euthyroid patients with no goiter

Exclusion Criteria:

• Pregnancy or lactation

• Severe lung or gasterointestinal disease

• Heart failure or renal failure