Effect of Celecoxib on Postoperative Analgesia and Disease Severity in AERD Patients With CRS
Status:
Recruiting
Trial end date:
2022-04-01
Target enrollment:
Participant gender:
Summary
This is a proposed randomized prospective study to evaluate both the anti-inflammatory and
analgesic effects of a COX-2 inhibitor, celecoxib, in patients with aspirin-exacerbated
respiratory disease and Chronic rhinosinusitis following endoscopic sinus surgery.
The investigators hypothesize that supplementation with celecoxib can potentially improve
surgical outcomes and reduce the postoperative usage of opioid analgesics without an
increased risk of bleeding or asthma exacerbation
Phase:
Phase 4
Details
Lead Sponsor:
Lawson Health Research Institute
Collaborators:
London Health Sciences Centre University of Western Ontario, Canada