Effect of Cilostazol on Coronary Artery Stenosis and Plaque Characteristics in Patients With T2DM

• Status: Completed
• Trial end date: 2016-11-01
• Target enrollment: 0
• Participant gender: All

Summary

This is a prospective interventional study to assess the effect of cilostazol compared with aspirin in Korean T2DM patients with atherosclerosis.

• Phase: Phase 3
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Seoul National University Bundang Hospital
• Treatments: Aspirin; Cilostazol

Criteria

Inclusion Criteria:

• Type 2 diabetes with HbA1c ≥ 6.0% at screening visit

• Male or female between 30 and 80 years of age

• Coronary artery stenosis: 25-75% without no evidence of acute coronary syndrome

• No history of previous myocardial infarction

• Estimated GFR ≥ 60 ml/min/1.73m²

Exclusion Criteria:

• SBP/DBP> 160/110

• Congestive heart failure

• Allegy to radiocontrast dye

• Allegy to aspirin or cilostazol

• Acute bleeding

• History of ulcer bleeding

• GOT/GPT > 100/100

• Other antiplatlet medication