Effect of Clonazepam on Cannabis Withdrawal and Relapse in Treatment-seeking Patients
Status:
Completed
Trial end date:
2020-06-01
Target enrollment:
Participant gender:
Summary
The proposed protocol is a double-blind, placebo-controlled inpatient and outpatient
study,looking at the clinical treatment of cannabis use disorder.
The treatment study is a total of 12 weeks. There will be two options offered to participants
for week 1 of the treatment study. 1) Patient will go inpatient for 5 nights and after
discharge from the inpatient phase will complete the 11-weeks of outpatient treatment or 2)
patients who cannot complete the inpatient phase due to work or other obligations will
complete the treatment 12-week study outpatient. 80 patients seeking treatment for cannabis
use disorder will be enrolled into either the inpatient/outpatient or only outpatient study.
This combined design will provide a comprehensive understanding of clonazepam's effects on
individuals with cannabis use disorder across a range of outcome measures while also testing
the medication's ability to prevent relapse in cannabis-abstinent patients.