Overview

Effect of Colchicine on the Progression of Aortic Valve Stenosis - A Pilot Study

Status:
Not yet recruiting
Trial end date:
2023-09-30
Target enrollment:
Participant gender:
Summary
COPAS pilot is a pilot single center double blinded randomized study to determine the effect of targeted anti-inflammation therapy using colchicine, on valvular calcification activity using imaging, i.e. aortic valvular NaF uptake. The current proposal uses a randomized design to evaluate the effect of colchicine vs. placebo on valvular calcification activity over 6 months measured using NaF PET
Phase:
Phase 2/Phase 3
Details
Lead Sponsor:
Ottawa Heart Institute Research Corporation
Treatments:
Colchicine