Effect of Colony Stimulating Factor on Implantation and Pregnancy Rates Following IVF (in Vitro Fertilization)

• Status: Completed
• Trial end date: 2013-06-01
• Target enrollment: 0
• Participant gender: Female

Summary

This a trial designed to test whether granulocyte colony stimulating factor (G-CSF, Neupogen) can increase the rate of embryo implantation following IVF and embryo transfer. Preliminary data at the Center for Human Reproduction(CHR) and elsewhere suggest that intrauterine infusion of G-CSF can improve endometrial development and can increase implantation rates of embryos.

• Phase: Phase 1/Phase 2
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Center for Human Reproduction
• Collaborator: Foundation for Reproductive Medicine
• Treatments: Lenograstim

Criteria

Inclusion Criteria:

• Women already enrolled in an IVF cycle at one of the participating institutions

Exclusion Criteria:

• Sickle Cell disease

• Renal insufficiency

• Upper respiratory infection or Pneumonia

• Chronic Neutropenia

• Known Past or present malignancy