Effect of Combined Antioxidant Therapy on Oxidative Stress Markers and Inflammatory Cytokines in Patients With Tinnitus
Status:
Recruiting
Trial end date:
2024-12-31
Target enrollment:
Participant gender:
Summary
The main objective of our study is to evaluate the effect of combinated antioxidants therapy
with Adepsique® (amitriptyline, perphenazine, and diazepam) on patients with tinnitus chronic
symptoms, evaluating the levels of inflammatory cytokines and oxidative stress in blood.
The researchers intend to include 58 patients, divided into two intervention groups, who will
be randomly assigned a pill with antioxidants or placebo, and the patient must eat one pill
per day for 3 months.
In the study, the clinical characteristics of tinnitus, inflammatory cytokines and oxidative
stress markers will be evaluated, before, during and after the intervention with antioxidant
therapy. Subsequently, the clinical and sample results will be evaluated to compare the
effects between them.
Phase:
Phase 2
Details
Lead Sponsor:
University of Guadalajara
Collaborators:
Hospital Civil de Guadalajara Institute of Experimental and Clinical Therapeutics