Effect of Continous Intravenous Lidocaine Infusion Intraoperative for Craniotomy Tumor Removal Surgery

• Status: Recruiting
• Trial end date: 2021-12-31
• Target enrollment: 0
• Participant gender: All

Summary

This study aimed to compare continous intravenous lidocaine infusion and placebo on the effect to brain relaxation, opioid consumption and postoperative cognitive status in adult patient undergoing craniotomy tumor removal surgery

• Phase: Phase 1/Phase 2
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Indonesia University
• Treatments: Lidocaine

Criteria

Inclusion Criteria:

• Adult patient age 18-65 years old undergo craniotomy tumor removal surgery

• Physical status ASA 1-3

• Compos mentis (GCS 15)

• Operation using pin head fixation

Exclusion Criteria:

• Patient or family refused to participate

• Has Atrioventricular block rhytm on ECG

• Has sign of circulation shock

• Midline shift > 5.4 mm on brain imaging

• Diagnose with Glioblastoma multiforme or Metastatic

• Vascular surgery

• Using CSF drainage (EVD, VP shunt, or Lumbal drain)

• Routine using or in treatmet using adrenergic agonist or antagonist drugs

• Routine consumption of opioid in last two weeks before surgery

• History of Local anesthetic hypersensitivity