Effect of Cranberry Extract on Infections in Burn Patients

• Status: Withdrawn
• Trial end date: 2013-10-01
• Target enrollment: 0
• Participant gender: All

Summary

Bacterial infections are a common complication in patients suffering from burns. These infections can cause significant morbidity and often mortality. Antimicrobial resistance coupled with the prevalence of burn-related infections warrants the identification of alternative substances in the treatment of burn-related infections. The cranberry has been examined as a potential agent in the prevention of other types of infections and it appears to have anti-adherence effects on bacteria. In addition, the cranberry has demonstrated general inhibitory effects against some types of bacteria suggesting that it may be a useful agent in the prevention of bacterial infections in burn patients. The purpose of the present study is to investigate the effect of cranberry extract on the incidence of infections in burn patients.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Saint Elizabeth Regional Medical Center

Criteria

Inclusion Criteria:

• Patients are admitted to the Saint Elizabeth Regional Medical Center Burn Unit.

• Age 19 and older.

• Patients have an expected hospital stay of 7 days or more.

• Patients are able to consume oral medication capsules.

Exclusion Criteria:

• Patients have a known infection.

• Patients are not able to consume oral medication capsules.

• Patients have any known allergies to cranberry or placebo components.

• Patients have known allergy to aspirin (cranberries may contain salicylic acid).

• Patients are pregnant or breast-feeding.

• Patients are taking warfarin

• Patients with known nephrolithiasis.

• Patients with renal impairment as evidenced by a creatinine clearance that is less than predicted by Cockroft-Gault formula.