Effect of Deep Neuromuscular Block (NMB), Inhalation or TIVA on Pneumoperitoneum.
Status:
Completed
Trial end date:
2016-04-01
Target enrollment:
Participant gender:
Summary
The objective of this study is to compare the value of deep neuromuscular block (NMB) (using
rocuronium) in laparoscopy versus high dose opioids (using remifentanil) or 1 minimum
alveolar concentration (MAC) inhalation (using sevoflurane) for the surgeon.
The study hypothesis is that laparoscopic workspace is larger when using rocuronium versus
opioids or inhalation. Laparoscopic workspace is measured as the abdominal compliance and the
pressure at volume zero (PV0) using the abdominal pressure volume relation. Three points
allow to calculate the abdominal compliance and the pressure at zero volume (PV0).