Effect of Deep Neuromuscular Block on Surgical Conditions in Morbidly Obese Patients

• Status: Completed
• Trial end date: 2016-04-01
• Target enrollment: 0
• Participant gender: All

Summary

This is a randomized control trial (RCT) that studies the surgical conditions during moderate and deep neuromuscular blockade in 100 morbidly obese patients receiving elective laparoscopic surgery for bariatric surgery.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Leiden University Medical Center
• Collaborators: Medical Center Haaglanden; Merck Sharp & Dohme Corp.
• Treatments: Rocuronium

Criteria

Inclusion Criteria:

• ASA I-III

• BMI > 34 kg/m2

• Elective bariatric surgery.

Exclusion Criteria:

• Known or suspected neuromuscular disorders impairing neuromuscular function

• Allergies to muscle relaxants, anesthetics or narcotics

• A(family) history of malignant hyperthermia

• Women who are or may be pregnant or are currently breast feeding

• Renal insufficiency, as defined by serum creatinine x 2 of normal, or urine output < 0.5 ml/kg/h for at least 6 h.