Overview

Effect of Deep Versus Moderate Neuromuscular Block During Sevoflurane Anesthesia on Intraoperative Surgical Conditions.

Status:
Completed
Trial end date:
2020-06-01
Target enrollment:
Participant gender:
Summary
A deep neuromuscular block (NMB) is often associated with improved surgical conditions especially in laparoscopic surgery. We previously showed that deep NMB is superior to a moderate NMB under propofol anesthesia. However, this may not apply to sevoflurane anesthesia and sevoflurane by itself produces some degree of muscle relaxation. We therefore plan to investigate the effect of deep NMB on surgical conditions under sevoflurane anesthesia maintenance.
Phase:
Phase 4
Details
Lead Sponsor:
Leiden University Medical Center
Collaborator:
Merck Sharp & Dohme Corp.
Treatments:
Rocuronium
Sevoflurane