Effect of Dexmedetomidine on Bispectral Index and Propofol Requirements During Different Menstrual Cycle

• Status: Completed
• Trial end date: 2012-11-01
• Target enrollment: 0
• Participant gender: Female

Summary

The study was done to evaluate the effects of the follicular and luteal phases of the menstrual cycle on sedation level at loss of consciousness and bispectral index reach to 50 during propofol anesthesia, in patients with and without preoperative intravenous dexmedetomidine .

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Fudan University
• Treatments: Dexmedetomidine; Propofol

Criteria

Inclusion Criteria:

• a regular menstrual cycle

• elective gynecologic surgery

Exclusion Criteria:

• pregnancy

• breastfeeding

• obesity

• known hypersensitivity to drugs used in the study protocol;

• use of psychotropic drugs and steroids within 72 hours before the surgery

• central nervous system injury

• renal impairment

• alcoholism and opioid addiction.