Effect of Dexmedetomidine on Left Ventricular Function in Coronary Artery Bypass Graft Surgery Outcome

• Status: Recruiting
• Trial end date: 2023-12-31
• Target enrollment: 0
• Participant gender: All

Summary

50 patients of both sexes undergoing elective CABG surgery will be randomly divided into 2 groups, study group (Dex) group and control group (C) to determine the effect of dexmedetomidine on the peri-operative hemodynamic changes during CABG surgery.

• Phase: Early Phase 1
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Ain Shams University
• Treatments: Dexmedetomidine

Criteria

Inclusion Criteria:

• undergoing elective CABG surgery

Exclusion Criteria:

• Patient refusal

• Dementia patients

• Poor ventricular function with ejection fraction below 40%

• Asthmatic patients

• Uncontrolled diabetic patients with HbA1c above 8

• Combined surgeries (CABG+ valves)

• Emergency surgeries.

• Pre-existing arrhythmia

• Patients with renal impairment

• Patients with hepatic impairment

• Patients with heart block

• Off-pump CABG