Effect of Different Courses of Lactobacilli Treatment on Bacterial Vaginosis and Pregnancy Outcomes

• Status: Unknown status
• Trial end date: 2012-05-01
• Target enrollment: 0
• Participant gender: Female

Summary

The purpose of this study is to examine the effect of lactobacillus preparation on Bacterial vaginosis (BV) in low-risk pregnant women and to evaluate the value of double courses for the patients with durative positive result. It is assumed that the living preparation of lactobacillus was beneficial for treatment of BV during pregnancy. The two-courses treatment can increase the response rate and improve pregnancy outcomes in the durative BV positive patients comparing with one-course one.

• Phase: Phase 1
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: The First Affiliated Hospital, Guangzhou University of Traditional Chinese Medicine
• Collaborator: Ministry of Health, China

Criteria

Inclusion Criteria:

• pregnant women at 16-18 gestational weeks with no history of premature labor or premature rupture of fetal membranes.

Exclusion Criteria:

• who have menstrual disorder or forget the last menstrual period, and have no type-B ultrasonic result, so the gestational week is not clear.

• Who have monilial vaginitis, trichomonas vaginitis, or sexual transmitted diseases.

• who have severe medicochirurgic diseases.

• multiple pregnancy.

• anomalies of genital tract

• fetal anomaly