Effect of Different Doses of Dexmedetomidine on Cerebral Oxygen Saturation and Postoperative Anxiety in Elderly Patients

• Status: Recruiting
• Trial end date: 2023-03-22
• Target enrollment: 0
• Participant gender: All

Summary

To investigate the effect of different doses of dexmedetomidine on Cerebral Oxygen Saturation and Postoperative anxiety in elderly patients undergoing laparoscopic surgery

• Phase: N/A
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: The First Hospital of Qinhuangdao
• Treatments: Dexmedetomidine

Criteria

Inclusion Criteria:

• Patients aged 65 years or older who underwent elective laparoscopic surgery under general anesthesia

• BMI less than 30 kg/m2

• American Society of Anesthesiologists (ASA) grades I-III

• The score of Mini Mental state examination≥24

Exclusion Criteria:

• Patients with heart, lung and other vital organ disorders

• The score of Mini Mental state examination≤23

• Preoperative psychiatric disorders or long-term use of drugs affecting the psychiatric system

• Have severe visual, hearing, speech impairment or other inability to communicate with the visitor

• Refuse to sign informed consent

• known preoperative left ventricular ejection fraction less than 30%, sick sinus syndrome, severe sinus bradycardia (<50 beats per min [bpm]), or second-degree or greater atrioventricular block without pacemaker