Effect of Doxepin and Nortriptyline on Irritable Bowel Syndrome
Status:
Completed
Trial end date:
1969-12-31
Target enrollment:
Participant gender:
Summary
The objective of this randomized triple blind controlled trial is to compare the effects of
Doxepin and Nortriptyline on diarrhea predominant irritable bowel syndrome. In this stuy, 75
patients with IBS are randomly assigned to receive Doxepin , Nortriptyline or placebo, a
tablet per day, orally, for two months. Abdominal pain, mucus in the stool, incomplete
evacuation, and bloating are measured and compared between groups at the baseline and one and
two month after the intervention.