Effect of Doxycycline in Levodopa Treated Parkinson's Disease Patients

• Status: Recruiting
• Trial end date: 2023-01-01
• Target enrollment: 0
• Participant gender: All

Summary

This study is a Randomized, Double-Blind, Placebo-Controlled Trial. The objective of the study is to assess the effect of doxycycline in levodopa treated Parkinson's disease patients regarding motor performance and cognitive functions. Parkinson's disease patients on levodopa medications will be assigned to receive doxycycline 50mg twice daily or placebo over 8 weeks. The motor and cognitive symptoms of Parkinson's disease will be assessed after 4 weeks and 8 weeks follow up.

• Phase: Phase 2
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh
• Treatments: Doxycycline

Criteria

Inclusion Criteria:

• Diagnosed Parkinson's disease patient taking Levodopa

• Age: More than 18 years

• Sex: All

Exclusion Criteria:

• Secondary causes of parkinsonism

• Atypical parkinsonian syndromes

• Prior stereotaxic surgery for Parkinson's disease

• Known hypersensitivity to doxycycline

• Pregnancy and lactation

• Suffering from active malignancy