Overview

Effect of Enalapril and Losartan Association Therapy on Proteinuria and Inflammatory Biomarkers in Diabetic Nephropathy: a Clinical Trial on Type 2 Diabetes Mellitus

Status:
Completed

Trial end date:
2007-09-01

Target enrollment:

Participant gender:

Summary

Chronic kidney disease (CKD)has become a significant health problem worldwide. Strategies to decrease the rate of progression of this disease and reduce the number of patients needing dialysis or renal transplantation are urgently needed. In this study we wish to compare the effect of dual blockade of renin-angiotensin system (ACE inhibitors plus angiotensin II receptor blocker) compared to the effect of ACE inhibitor monotherapy in patients with diabetic chronic nephropathy.

Phase:

Phase 4

Details

Lead Sponsor:

University of Sao Paulo

Collaborator:

Fundação de Amparo à Pesquisa do Estado de São Paulo

Treatments:

Enalapril
Enalaprilat
Losartan