Effect of Erythropoietin in Premature Infants on White Matter Lesions and Neurodevelopmental Outcome
Status:
Unknown status
Trial end date:
2019-06-01
Target enrollment:
Participant gender:
Summary
Preterm and very preterm infants are at risk of developing encephalopathy of prematurity and
long-term neurodevelopmental delay. Magnetic resonance imaging (MRI) allows the
characterization of specific features of encephalopathy of prematurity, including structural
changes of brain white matter and gray matter. This study wants to investigate important
evidence that early repeated high-dose rhEPO(5250 IU/kg) treatment improves long-term
neurological outcomes in very preterm infants and without obvious adverse effects.
Phase:
Phase 3
Details
Lead Sponsor:
First Affiliated Hospital Xi'an Jiaotong University
Collaborators:
Northwest Women and Children's Hospital Second Affiliated Hospital of Xi'an Jiaotong University Second Affiliated Hospital of Xi'an Medical University Shaanxi Provincial People's Hospital Tang-Du Hospital Xi'an Children's Hospital Xi'an No.4 Hospital Xian Children's Hospital Xijing Hospital