Overview

Effect of Esmolol on Perioperative Stress Reaction

Status:
Not yet recruiting
Trial end date:
2023-12-31
Target enrollment:
0
Participant gender:
All
Summary
The goal of this clinical trial is to observe the effect of low dose continuous infusion of esmolol on perioperative stress response in patients undergoing airway intervention .
Phase:
Phase 4
Accepts Healthy Volunteers?
No
Details
Lead Sponsor:
Xiumei Song
Treatments:
Esmolol
Criteria
Inclusion criteria

1. American Society of Anesthesiologists (ASA) Physical Status I to III.;

2. Body mass index (BMI): 20-30 kg/m2;

3. Elective airway intervention under general anesthesia with jet ventilation,duration of
operation less than 2hs;

4. Sign informed consent for clinical trial

Exclusion criteria

1. The patient and his or her family refused to participate in the study;

2. Severe respiratory or/cardiovascular or/ neurological disease, or/ hepatic or/renal
dysfunction

3. Those who are allergic to the drugs used in this study;

4. Psychiatric history or with unstable mental state;

5. Patients with atrioventricular block

6. Patients with history of asthma

7. Patients now treated with β-adrenergic receptor blockers

8. Patients participating in other clinical trial