Effect of Estradiol Pretreatment on Antagonist ICSI Cycles

• Status: Completed
• Trial end date: 2021-11-15
• Target enrollment: 0
• Participant gender: Female

Summary

Depended on the hypothesis that growth asynchrony of antral follicles is a consequence of the gradual FSH elevation that occurs during the late luteal phase, the aim of this work is to study the effect of estradiol pretreatment on follicular synchronization and intracytoplasmic sperm injection (ICSI) outcome in antagonist cycles

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Alexandria University
• Treatments: Estradiol; Estradiol 17 beta-cypionate; Estradiol 3-benzoate; Polyestradiol phosphate

Criteria

Inclusion Criteria:

1. Women age 20-37 years.

2. AMH level greater than 1.2 ng/ml.

3. Body mass index between 18 and 29 kg/m2.

4. Undergoing a first or second ICSI cycles.

Exclusion Criteria:

1. Endometriosis.

2. Uterine disorders such as fibroids and uterine anomalies.

3. Antral follicular counts (AFC) less than 10.

4. Azospermic males.