Effect of Ezetimibe on Flow-mediated Brachial Artery Reactivity in Healthy Subjects

• Status: Completed
• Trial end date: 2008-04-01
• Target enrollment: 0
• Participant gender: All

Summary

The objective of this study is to show that Ezetimibe will improve endothelial function following high cholesterol meals in healthy subjects by decreasing absorption of cholesterol and thus affecting concentration and composition of remnant-like particles.

• Phase: Phase 4
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: University of California, San Diego
• Treatments: Ezetimibe

Criteria

Inclusion Criteria:

• healthy adults over 18 yrs of age

Exclusion Criteria:

• presence of known metabolic syndrome

• as history of coronary artery disease

• hypertension

• diabetes

• cardiomyopathy

• tobacco use