Overview

Effect of Fentanyl on the Rate of Anesthesia

Status:
Completed
Trial end date:
2013-01-01
Target enrollment:
0
Participant gender:
All
Summary
Achievement of a deep and long-durated anesthesia is vital before most endodontic procedures; therefore, the investigators conducted this study to compare the local infiltration effect of epinephrine-containing lidocaine with/ without fentanyl on depth and duration of anesthesia in maxillary molars with painful irreversible pulpitis.
Phase:
Phase 2
Accepts Healthy Volunteers?
Accepts Healthy Volunteers
Details
Lead Sponsor:
Islamic Azad University, Tehran
Treatments:
Epinephrine
Epinephryl borate
Fentanyl
Lidocaine
Racepinephrine
Criteria
Inclusion Criteria:

- Patients were aged between 18 and 65 years with no systemic diseases categorized in
the Class I ASA;

- Individuals requiring urgent root canal treatment of maxillary first or second molars;

- Hot painful teeth with irreversible pulpitis (moderate to severe spontaneous pain),
with a positive response to thermal vitality tests (a long painful response to a cold
test) and no clinical or radiographic signs or symptoms of acute or chronic apical
periodontitis; and

- No history of taking analgesics in the previous 12 h.

Exclusion Criteria:

- Systemic conditions;

- Allergic reactions to opioids, benzodiazepines, barbiturates;

- Pregnancy and lactation; Contraindication of the use of epinephrine (such as unstable
angina);

- Nonvital pulp after access cavity preparation