Effect of Fish Oil on Adiposity and Atherogenic Factors in Type 2 Diabetic Women

• Status: Terminated
• Trial end date: 2005-04-01
• Target enrollment: 0
• Participant gender: Female

Summary

1. whether the intake of n-3 PUFA has additional effects on insulin sensitivity and adiposity (total fat mass and adipocyte morphology and function) in T2D women.

2. n-3 PUFA supplementation might influence inflammatory genes expression in the adipose tissue of T2D patients.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Assistance Publique - Hôpitaux de Paris
• Collaborator: Institut National de la Santé Et de la Recherche Médicale, France

Criteria

Inclusion Criteria:

1. Type 2 diabetic postmenopausal women

2. glycaemia of 7.87-14.0 mmol/l, HbA1c of 7 to 10.5%

3. plasma triglycerides between 1.72-4.6 mmol/l,

4. aged between 40 -60,

5. BMI: 27-40 kg/m2

6. able to swallow tablets

Exclusion Criteria:

1. patients with abnormal renal, hepatic and thyroid functions as determined by physical examination, blood cell count and standard blood biochemical profile

2. patients with gastrointestinal disorders

3. patients treated with thiazolidinediones or insulin