Effect of Fixed Brinzolamide-brimonidine Combination on Intraocular Pressure After Phacoemulsification

• Status: Completed
• Trial end date: 2018-04-06
• Target enrollment: 0
• Participant gender: All

Summary

This study aims to evaluate the effect of fixed brinzolamide-brimonidine combination on intaocular pressure after uncomplicated phacoemulsification surgery.

Patients scheduled for phacoemulsification will be randomly assigned to 1 of 2 groups.

The treatment group will receive 1 drop of brimonidine-brinzolamide fixed combination immediately after surgery, and the control group will receive no treatment. The IOP will be measured preoperatively and at 6, 12, and 24 hours postoperatively.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: University Hospital of Patras
• Treatments: Brimonidine Tartrate; Brinzolamide

Criteria

Inclusion Criteria:

• Patients scheduled to undergo cataract surgery by phacoemulsification.

Exclusion Criteria:

• previous ocular surgery

• ocular hypertension

• pseudoexfoliation syndrome

• pigment dispersion syndrome

• glaucoma

• history of severe cardiovascular disease, cerebral or coronary insufficiency, depression, Raynaud's phenomenon, orthostatic hypotension or thromboangiitis obliterans

• hypersensitivity to sulfonamides or brimonidine