Effect of Folic Acid Supplementation on Plasma Homocysteine Level in Obese Children

• Status: Completed
• Trial end date: 2013-03-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of the present study was to determine whether folic acid supplementation could reduce plasma homocysteine in obese children and to determine the association between dietary folate, serum folate and homocysteine level through the randomized double blinded placebo controlled trial.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Queen Sirikit National Institute of Child Health
• Collaborator: Chulalongkorn University
• Treatments: Folic Acid; Vitamin B Complex

Criteria

Inclusion Criteria:

• Patient age between 9-18 years

• Diagnosed obesity (BMI more than median plus two of standard deviation for age and sex according to WHO reference 2007)

Exclusion Criteria:

• Secondary obesity

• Thalassemia disease

• Renal and hepatic dysfunction

• Drugs: anticonvulsant, estrogen, thiazides, metformin, cholestyramine, methotrexate, fibrates, nicotinic acid

• Previous vitamin supplementation 1 month before study