Effect of Fully Blocking Type 1 Angiotensin Receptor on Target Organ Damage of Postmenopausal Hypertensive Women

• Status: Unknown status
• Trial end date: 2019-08-01
• Target enrollment: 0
• Participant gender: All

Summary

This study compared the improvements of blood pressure levels, left ventricular hypertrophy, left ventricular diastolic function, vascular function and cognitive function between postmenopausal hypertensive women and age-matched hypertensive male patients through the evaluation of the effects of fully blocked AT1 receptor by valsartan. Additionally, the differences of the above indexes between the patients who were fully blocked AT1 receptor by valsartan and the patients who were treated with a single dose of valsartan treatment were assessed, so as to provide theory basis for clinical treatment of postmenopausal hypertensive women.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: LanZhou University
• Treatments: Valsartan

Criteria

Inclusion Criteria:

• Clinical diagnosis of hypertension

• Women are all postmenopausal

• Must provide written informed consent

Exclusion Criteria:

• Secondary hypertension

• Coronary disease

• Heart failure

• Arterial fibrillation

• Previous myocardial infarction

• Previous stroke

• Malignant disease

• Kidney failure

• Liver failure

• Neoplastic disease

• Severe neurological diseases

• Severe metabolic or organic decompensation

• Refuse to sign the informed consent form