Effect of GABAB Agonist on Visceral Hyperalgesia in NCCP patientsChinese?
Status:
Terminated
Trial end date:
2007-01-01
Target enrollment:
Participant gender:
Summary
The effect of baclofen (GABAB agonist), diltiazem (muscle relaxant) and placebo will be
compared in a double-blinded randomized study for the treatment of NCCP. Cerebral cortical,
brainstem and spinal evoked potentials before and after treatment will be evaluated. Results
of this study will shed lights on pathogenesis and treatment of NCCP in Chinese.We
hypothesize that Baclofen alleviates visceral hyperalgesia in NCCP patients by suppressing
afferent sensory pathway.