Effect of Glutathione vs KI in Reducing SDF Staining When Used in Treatment of Primary Carious Teeth

• Status: Not yet recruiting
• Trial end date: 2022-05-01
• Target enrollment: 0
• Participant gender: All

Summary

Although black staining is considered a drawback that is clinically observed following SDF application and is the main primary barrier for its use clinically . Child's behaviour and cooperation cannot be controlled at a young age or in special health care needs cases. Therefore, the best treatment modality will always be a simple, fast and painless procedure and SDF is the best solution for those cases. Discolouration caused researchers to search for a solution that will reduce or prevent discolouration using KI and GSH. A systematic review was conducted in-vitro, and it showed the use of SDF with KI had reduced stains markedly, potential advantages of minimal staining might be advantageous, along a short period. However, studies with long-term follow-up would be required to provide evidence-based guidelines for using SDF and KI formulations in routine clinical practice

• Phase: N/A
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Cairo University

Criteria

Inclusion Criteria:

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Children:

• Aged 3 to 5 years, in good general health and medically free.

• The parents provided written informed consent.

• Medically free

Teeth:

• Carious primary teeth

• Restorable teeth.

• Teeth are not pulpally involved

Exclusion Criteria:

• Children:

• with a history of allergy to silver

• Unable to attend follow-up visits.

• Refusal of participation.

Teeth:

• Previously restored teeth.

• Periapical swelling and tenderness in this area.

• With mobility.

• With spontaneous pain.