Effect of GnRH Antagonist vs Agonist Long on IVF Outcome, Peak Estradiol Level,and Duration of Stimulation

• Status: Completed
• Trial end date: 2014-05-01
• Target enrollment: 0
• Participant gender: Female

Summary

The purpose of this study is to determine if utilizing GnRH antagonists versus agonist long protocol during controlled ovarian stimulation (COH) with human-derived gonadotropins for assisted reproduction affects IVF outcome, peak estradiol level, and duration of stimulation.

• Phase: N/A
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Main Line Fertility Center
• Collaborator: Ferring Pharmaceuticals
• Treatments: Cetrorelix; Estradiol; Ganirelix; Leuprolide; Menotropins

Criteria

Inclusion Criteria:

• Ages 21-40 (inclusive up to 41)

• Day 2-4 FSH < or equal to 10

• Antimullerian Hormone (AMH) greater than or equal to 1.0

• Between 5 and 20 antral follicles on day 2-4

• Body Mass Index (BMI)>or equal to 18 and < or equal to 32

Exclusion Criteria:

• Smokers

• Polycystic Ovarian Disease

• Endometriosis greater than Stage I

• Testicular aspirated sperm