Effect of Gui-Lu-Er-Xian-Jiao-Wan on Intradialytic Hypotension

• Status: Not yet recruiting
• Trial end date: 2024-12-31
• Target enrollment: 0
• Participant gender: All

Summary

Intradialytic hypotension (IDH), a common complication during hemodialysis (HD) could increase patients' morbidity and mortality. Previous studies considered that some Chinese herbal medicine (CHM) plays a complementary role in reducing the frequency of IDH. This trial is aimed to investigate the effect of Gui-Lu-Er-Xian-Jiao-Wan (GLEXJW) in patients with intradialytic hypotension.

• Phase: Phase 2/Phase 3
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Chang Gung Memorial Hospital

Criteria

Inclusion Criteria:

• End stage renal disease treated with hemodialysis for ≥3 months

• Receive a standard thrice-weekly hemodialysis schedule

• More than 25% of hemodialysis sessions complicated by intradialytic hypotension

Exclusion Criteria:

• Active malignancy

• Life-threatening conditions

• Pregnancy

• Recent participation in another clinical trial for intradialytic hypotension

• History of hypersensitivity or contraindication to herbal medicine