Effect of Hydrocortison on Post-ischemic Flow-mediated Dilation and on Thenar Oxygen Saturation in Human Septic Shock.
Status:
Terminated
Trial end date:
2019-11-05
Target enrollment:
Participant gender:
Summary
The main objectives of the study are 1)to examine the immediate (2 hours) and delayed (8
hours) effects of intravenous hydrocortison on macro and microvascular post-ischemic
vasoreactivity, in septic shock adult patients; 2) to examine possible correlations between
post-ischemic flow-mediated dilation (FMD) of the brachial artery (assessed by ultrasound
imaging) and post-ischemic recovery slope of the thenar oxygen saturation (StO2) (assessed by
near-infrared spectroscopy).