Effect of Ibuprofen on Postoperative Opiate Medication Use and Shoulder

• Status: Active, not recruiting
• Trial end date: 2022-10-01
• Target enrollment: 0
• Participant gender: All

Summary

This will be a randomized controlled trial to determine if postoperative ibuprofen after arthroscopic rotator cuff repair impacts postoperative opiate medication use, Visual Analog Scale (VAS) pain scores, shoulder range of motion (ROM), and repair integrity.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: University of California, San Francisco
• Treatments: Acetaminophen; Acetaminophen, hydrocodone drug combination; Hydrocodone; Ibuprofen; Oxycodone

Criteria

Inclusion Criteria:

• Patients 18 years or older

• Patients that undergo arthroscopic rotator cuff repair only

Exclusion Criteria:

• Patients less than 18 years of age, pregnant, are incarcerated. Women who are not post-menopause are screened for pregnancy preoperatively with a urine test per our UCSF Orthopaedic Institute preoperative guidelines.

• Patients who are unable to and not willing to comply with the study protocol and follow-up visits

• Patients with a history of prior rotator cuff repair

• Patients with rotator cuff tears that require open repair

• Patients with an allergy to ibuprofen or anti-inflammatory medications

• Patients with a medical chart record or those who report a history of upper gastroenterology bleed or gastic ulcers

• Patients who are currently on warfarin, enoxaparin, heparin, or a factor Xa inhibiting anti-coagulation medication

• Patients with a known past medical history of chronic kidney disease, history of kidney transplant, or eGFR < 60 mL/min per 1.73m2.