Effect of Injectable Platelet-Rich Fibrin (i-PRF) in Initial Treatment of Chronic Periodontitis

• Status: Completed
• Trial end date: 2020-07-09
• Target enrollment: 0
• Participant gender: All

Summary

Current treatments of periodontitis have limited efficacy since they fail to suppress microorganisms satisfactorily over time. The aim of present study was to investigate whether there are differences between initial treatment of chronic periodontitis (SRP) and SRP in conjunction with injectable platelet-rich fibrin (i-PRF) application.

• Phase: Phase 4
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: University of Belgrade

Criteria

Inclusion Criteria:

• A minimum of 6 teeth per quadrant;

• A minimum of 2 teeth in each quadrant with a probing depth (PD) ≥5 mm;

• Bleeding on probing (BOP) had to be at ≥40% tooth sites;

• No involvement of furcation;

• Good general health.

Exclusion Criteria:

• Periodontal therapy within last 12 months;

• Having surgical therapy;

• Use of antibiotics over the last 6 months;

• Ongoing drug therapy that might have an impact on the clinical signs and symptoms of periodontitis;

• Pregnancy or nursing;

• Current and former smokers.