Effect of Insulin Sensitization on IGF-1 Response to Growth Hormone in SGA Children
Status:
Unknown status
Trial end date:
2020-06-01
Target enrollment:
Participant gender:
Summary
This study is aimed to determine if Metformin treatment in children born small for
gestational age (SGA) who are being treated with Growth Hormone (GH) for short stature
improves the response to GH by producing greater concentrations of Insulin-like growth factor
-1 (IGF-1) in the blood.
Phase:
N/A
Details
Lead Sponsor:
Cambridge University Hospitals NHS Foundation Trust
Collaborators:
Birmingham Children's Hospital NHS Foundation Trust Birmingham Women's and Children's NHS Foundation Trust Department of Growth and Reproduction, Rigshospitalet, Copenhagen, Denmark Rigshospitalet, Denmark The National Children's Hospital, Tallaght