Overview
Effect of Intranasal Administration of Orexine A on IL-6-System, Sleep-Wake-Regulation and Neurocognition
Status:
Unknown status
Unknown status
Trial end date:
2009-08-01
2009-08-01
Target enrollment:
0
0
Participant gender:
All
All
Summary
15 patients with narcolepsy and 15 healthy controls will be included in the study. According to a randomized, double-blind protocol they will receive intranasally at night first Orexine A and approximately two weeks later placebo or vice versa. Thereafter sleep will be recorded, the cytokine-system and neurocognition characterized.Phase:
N/AAccepts Healthy Volunteers?
Accepts Healthy VolunteersDetails
Lead Sponsor:
Zentrum für Integrative Psychiatrie
Criteria
Inclusion Criteria:- Narcolepsy
- Age >18
- Informed consent
- GERMAN fluently spoken
Exclusion Criteria:
- Additional severe psychiatric or somatic disorders
- Pregnancy or nursing
- Anemia (Hb<10g/dl)